Rosanna Lisa Arquette (/roʊˈzænə ɑːrˈkɛt/; born August 10, 1959) is an American actress. She was nominated for an Emmy Award for her performance in the TV film The Executioner's Song (1982) and won the BAFTA Award for Best Actress in a Supporting Role for the film Desperately Seeking Susan (1985). Her other film roles include After Hours (also 1985), The Big Blue (1988), Pulp Fiction (1994), and Crash (1996). She also directed the documentary Searching for Debra Winger (2002) and starred in the ABC sitcom What About Brian? from 2006 to 2007.

Early life
Arquette was born in New York City on August 10, 1959, the daughter of Brenda Olivia "Mardi" (née Nowak), an actress, poet, theater operator, activist, acting teacher, and therapist, and Lewis Arquette, a film actor, screenwriter, and producer. Her paternal grandfather was comedian Cliff Arquette. Her mother was Jewish, from a family that emigrated from Poland and Russia. Her father, whose original family surname was "Arcouet", was of part-French-Canadian descent. Her father was a convert from Catholicism to Islam. Her siblings, Richmond, Patricia, Alexis, and David, all became actors as well.