Donna Biscoe (born September 30, 1955) is an American actress.

Early years
Biscoe was born in Fort Benning, Georgia, the daughter of Mildred Skillern, a retired Carver High School English teacher. Biscoe attended Carver, then graduated from Kendrick High School in Columbus in 1973 and later graduated from Clark Atlanta University with a bachelor's degree in elementary education. Biscoe later went to Lee Strasberg Theatre and Film Institute in New York for six months.

In the 1980s, a casting agent discovered Biscoe while she worked as a flight attendant for Eastern Airlines.