Isaiah Washington IV is an American actor and media personality. Following a series of film appearances, he came to prominence for portraying Dr. Preston Burke in the first three seasons of the series Grey's Anatomy from 2005 to 2007.

Washington began his career collaborating with director Spike Lee on the films Crooklyn (1994), Clockers (1995), Girl 6 (1996), and Get on the Bus (1996). He also appeared in the films Love Jones (1997), Bulworth (1998), True Crime (1999), Romeo Must Die (2000), Exit Wounds (2001), Ghost Ship (2002), and Hollywood Homicide (2003). In 2005, Washington landed his breakthrough role as Preston Burke on Grey's Anatomy. He was dismissed after the third season due to his usage of a homophobic slur while referring to a cast member, T. R. Knight, although he would return for a guest appearance in 2014. From 2014 to 2018, Washington portrayed Thelonious Jaha on The CW's science fiction television series The 100.

In 2020, Washington became the host of a travel cooking show on Fox Nation.

Early life
Washington was born in Houston, Texas, where his parents were residents in the Houston Heights community. His parents moved to Missouri City, Texas around 1980, where he was one of the first graduates from Willowridge High School, Houston, in 1981. Washington revealed in an interview with Star Jones that his father, after whom he was named, was murdered when he was 13 years old. He joined the United States Air Force when he was 19 years old, where he worked on the Northrop T-38 Talon. His first assignment was at Clark Air Base in the Philippines followed by two years at Holloman Air Force Base in Alamogordo, New Mexico. After serving in the Air Force, he attended Howard University.