Regina Cassandra (born 11 December 1988) is an Indian actress who primarily works in Tamil and Telugu films. She made her acting debut with the Tamil film Kanda Naal Mudhal (2005) and made her Telugu film debut with Siva Manasulo Sruthi (2012), for which she won the SIIMA Award for Best Female Debut - Telugu. She made her Hindi film debut with Ek Ladki Ko Dekha Toh Aisa Laga (2019).

Cassandra initially worked in successful films including Routine Love Story (2010), Kedi Billa Killadi Ranga (2013), Power and Pilla Nuvvu Leni Jeevitham both (2014). She received praises for her portrayal of a traditional girl in Subramanyam for Sale (2015), a dental student in Jyo Achyutananda (2016), a youngster in Maanagaram (2017) and a drug addict in Awe (2018). She received SIIMA Award for Best Actress – Telugu nomination for Jyo Achyutananda. Cassandra received SIIMA Award for Best Actor in a Negative Role nomination for her portrayal of a businesswoman in Evaru (2019). Further success came with Silukkuvarupatti Singam (2018), Nenjam Marappathillai, Mughizh both (2021) and Saakini Daakini (2022). She made her web debut with Rocket Boys (2022), for which she received Filmfare OTT Best Supporting Actor - Female nomination.

Cassandra is a CineMAA Awards and a Zee Telugu Apsara Awards recipient. In addition to her acting career, she is a prominent celebrity endorser for brands and products.

Early life
Regina Cassandra was born on 13 December 1988 in Madras (now Chennai), India. Her mother tongue is Tamil.